Downstream / DSP products
GMP buffers, stock solutions, reagents and formulation excipients for biologic purification - 32 catalogue products, each with its own article number and product page.
Every downstream article, by function
Same products as the Open Downstream system, listed here for direct browsing. One stocked size per product (500 ml or 100 ml) with its article number; 1000 ml bottles and 1-1000 L single-use bags on request; a WFI Beyond version of every buffer on request. Click any product for composition, pack size and ordering.
Foundation - water & isotonic bases3 products
Salts & ionic-strength stocks4 products
pH / buffering stocks8 products
- Tris Buffer 1 M, pH 8.4CT-05500Equilibration, neutralisation, AEX, TE/lysis base
- Phosphate Buffer 100 mMCT-18810AEX, polishing, formulation
- Sodium Acetate 100 mM, pH 4.5CT-76451CEX, UF/DF, formulation
- Citrate Buffer 100 mM, pH 3.0CT-62500Protein A elution + low-pH viral inactivation
- Glycine 100 mM Buffer, pH 3.0CT-69500Alternative Protein A elution / low-pH hold
- Histidine 100 mMCT-69510SEC, UF/DF, primary mAb formulation buffer
- HEPES Buffer 1 MCT-01100pH stabilisation for handling / sampling
- Sodium citrate, neutral (~pH 6.5)CT-62310mRNA storage; general neutral-citrate buffering
Chelation, lysis & nucleic-acid clearance6 products
- EDTA 0.5 M, pH 8.0CT-10500Chelation, equilibration, elution, endotoxin removal
- Triton X-100 10% SolutionCT-01001Lysis, enveloped-virus inactivation, dsRNA control
- Endonuclease SolutionCT-77351Host-cell / residual DNA-RNA digestion; nucleic-acid clearance
- Potassium acetate 3 M, pH 5.5CT-76500Alkaline-lysis neutralisation (pDNA)
- SDS 10%CT-06500Alkaline cell lysis (pDNA)
- Triton CG-110 (xenofree)CT-01101Xenofree detergent for animal-free platforms
CIP, sanitisation & storage2 products
Stabilisers & formulation excipients9 products
- Sucrose 30% Stock SolutionCT-00131Cryo-/lyo-protectant, stability excipient
- Trehalose 30% Stock SolutionCT-00231Alternative cryoprotectant (lyo / SC)
- Polysorbate 20 (PS20) 1%CT-00211Anti-aggregation surfactant (IV mAb)
- Polysorbate 80 (PS80) 1%CT-00311Surfactant (SC / lyo)
- Glucose 20% Stock SolutionCT-00331Process additive / feed
- L-Arginine 1 M, pH 7.0CT-69520Viscosity / aggregation control in high-conc mAb
- Mannitol 10% (w/v)CT-00401Bulking agent for lyophilised products
- Recombinant human serum albumin (rHSA)CT-27500Animal-free stabiliser for vectors, cell products
- Glycerol 20% (v/v)CT-00901Cryoprotectant for viral vectors / cell banks
Frequently asked questions
What is in the Downstream / DSP product range?
32 GMP downstream products across six functional families - water and isotonic bases, salts and ionic-strength stocks, pH / buffering stocks, chelation / lysis / nucleic-acid clearance, CIP and storage, and formulation excipients. Each has its own product page with composition, pack size and article number.
How does this relate to The Open Downstream page?
Same products, two views. This Products category lists every DSP article for direct browsing; The Open Downstream page (/downstream/) puts them in process context - which product is used at which purification step - plus applications, whitepapers and case studies.
How do I order, and what pack size will I receive?
Each article number corresponds to one stocked pack size - 500 ml for high-volume buffers, salts, CIP reagents and water; 100 ml for concentrated excipients and additives. Order by article number; in-stock items are dispatched worldwide within 24 hours. 1000 ml bottles and single-use bags from 1 L to 1000 L are quoted on request.
Are these products GMP grade, and is a Certificate of Analysis included?
Yes - catalogue GMP, manufactured by PAN-Celltech to GMP in an EU Annex 1 facility within an ISO 9001 quality system. A Certificate of Analysis ships with every lot. DPBS (CT-36500) and WFI Beyond are additionally backed by filed FDA Type IV Drug Master Files.
Can I get a beyond-compendial or custom version?
Yes. Every downstream buffer is available in a beyond-compendial version produced with WFI Beyond on request, and any product can become a fully customized GMP formulation to your own recipe.