Upstream & Downstream

Phosphate Buffer 100 mM

100 mM phosphate buffer for anion-exchange, polishing and formulation buffer systems. · GMP catalogue product · CT-18810

GMP · CT-18810Downstream · DSP

Phosphate Buffer 100 mM is a defined phosphate buffer for downstream processing. It is a versatile base for anion-exchange (AEX), polishing and formulation buffer systems. As a GMP-grade buffer it is used across monoclonal antibodies, vaccines, mRNA and cell & gene therapy.

One GMP quality. Phosphate Buffer 100 mM is a GMP-grade catalogue product (CT-18810), manufactured by PAN-Celltech and released against a defined quality-control panel on every lot.

Why

  • Versatile phosphate base - AEX, polishing and formulation.
  • Defined composition - 100 mM phosphate system.
  • GMP grade - Catalogue GMP quality, released per lot.
  • Multi-application - Used across antibody, vaccine, mRNA and C&G downstream.

Specification

Composition100 mM phosphate
FormReady-to-use buffer
Storage15-25 °C (room temperature)
GradeGMP

Ordering

GradeArticle No.Pack size
GMPCT-18810100 ml

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Other pack sizes are available on request.

Beyond compendial - on request. Every PAN downstream buffer is also available in a beyond-compendial version produced with WFI Beyond - Water for Injection engineered beyond the Ph. Eur./USP monograph - for the most demanding endotoxin and purity requirements. Available on request.

In the downstream process - by application

Phosphate Buffer 100 mM is used at the following process steps across the four biologics platforms:

Monoclonal antibodies

  • Anion exchange (AEX) - equilibration and wash buffer base.
  • SEC polishing - running buffer.
  • Formulation - phosphate buffer base.

Vaccines

  • Ion-exchange chromatography - buffer base.
  • Formulation - phosphate buffering.

mRNA

  • Buffer exchange - phosphate buffering.
  • Formulation - buffer base.

Cell & gene therapy

  • Anion exchange - equilibration and wash.
  • Polishing / formulation - buffer base.

Frequently asked questions

What is Phosphate Buffer 100 mM used for?

It is a base for anion-exchange (AEX), polishing and formulation buffer systems.

Is it multi-application?

Yes, it is used across monoclonal antibodies, vaccines, mRNA and cell & gene therapy downstream.

One partner across every application. The same GMP downstream buffers support monoclonal antibodies, vaccines, mRNA and cell & gene therapy - explore the full GMP-grade catalogue or use the Smart Product Search.