Upstream & Downstream

Polysorbate 80 (PS80) 1 %

1 % polysorbate 80 surfactant stock to prevent protein aggregation and surface adsorption. · GMP catalogue product · CT-00311

GMP · CT-00311Downstream · DSP

Polysorbate 80 (PS80) 1 % is a defined surfactant stock for downstream processing. Added in UF/DF and final formulation, it protects proteins from aggregation and interface/adsorption stress. As a GMP-grade stock it is applied across monoclonal antibodies, vaccines, mRNA and cell & gene therapy.

One GMP quality. Polysorbate 80 (PS80) 1 % is a GMP-grade catalogue product (CT-00311), manufactured by PAN-Celltech and released against a defined quality-control panel on every lot.

Why

  • Protects protein at interfaces - Prevents aggregation and adsorption.
  • Concentrated 1 % stock - Easy to dose into the formulation.
  • GMP grade - Catalogue GMP quality, released per lot.
  • Multi-application - Formulation surfactant across platforms.

Specification

Composition1 % (w/v) polysorbate 80
FormSurfactant stock
Storage15-25 °C (room temperature); protect from light
GradeGMP

Ordering

GradeArticle No.Pack size
GMPCT-00311100 ml

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Other pack sizes are available on request.

Beyond compendial - on request. Every PAN downstream buffer is also available in a beyond-compendial version produced with WFI Beyond - Water for Injection engineered beyond the Ph. Eur./USP monograph - for the most demanding endotoxin and purity requirements. Available on request.

In the downstream process - by application

Polysorbate 80 (PS80) 1 % is used at the following process steps across the four biologics platforms:

Monoclonal antibodies

  • UF/DF and final formulation - anti-aggregation / anti-adsorption surfactant.

Vaccines

  • Formulation - surfactant / emulsion aid.

mRNA

  • LNP / final formulation - surfactant.

Cell & gene therapy

  • Vector formulation - surfactant.

Frequently asked questions

What is Polysorbate 80 (PS80) 1 % used for?

It is a surfactant stock added in formulation to protect proteins from aggregation and interface stress.

Is it multi-application?

Yes, it is used across monoclonal antibodies, vaccines, mRNA and cell & gene therapy downstream.

One partner across every application. The same GMP downstream buffers support monoclonal antibodies, vaccines, mRNA and cell & gene therapy - explore the full GMP-grade catalogue or use the Smart Product Search.