Upstream & Downstream

L-Arginine 1 M, pH 7.0

1 M L-arginine at pH 7.0 for viscosity and aggregation control in high-concentration formulation. · GMP catalogue product · CT-69520

GMP · CT-69520Downstream · DSP

L-Arginine 1 M, pH 7.0 is a defined arginine concentrate for downstream processing and formulation. It controls viscosity and aggregation in high-concentration antibody formulations and serves as an elution and refolding additive - used mainly in antibody and cell & gene therapy workflows.

One GMP quality. L-Arginine 1 M, pH 7.0 is a GMP-grade catalogue product (CT-69520), manufactured by PAN-Celltech and released against a defined quality-control panel on every lot.

Why

  • Aggregation control - reduces aggregation in high-conc. formulation.
  • Viscosity reduction - for high-concentration products.
  • GMP grade - for regulated processing.
  • Multi-application - mAb and C&G.

Specification

Composition1 M L-arginine (as arginine·HCl)
pH7.0
Storage15-25 °C (room temperature)
FormStock concentrate
GradeGMP

Ordering

GradeArticle No.Pack size
GMPCT-69520100 ml

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Other pack sizes are available on request.

Beyond compendial - on request. Every PAN downstream buffer is also available in a beyond-compendial version produced with WFI Beyond - Water for Injection engineered beyond the Ph. Eur./USP monograph - for the most demanding endotoxin and purity requirements. Available on request.

In the downstream process - by application

L-Arginine 1 M, pH 7.0 is used at the following process steps across the four biologics platforms:

Monoclonal antibodies

  • High-concentration formulation - viscosity and aggregation control.
  • Chromatography - elution / refolding additive where used.

Vaccines

  • Not typically used in this modality.

mRNA

  • Not typically used in this modality.

Cell & gene therapy

  • Formulation - aggregation control where used.

Frequently asked questions

What is L-Arginine 1 M used for?

It controls viscosity and aggregation in high-concentration formulations and is an elution/refolding additive.

What is the pH?

It is supplied at pH 7.0.

One partner across every application. The same GMP downstream buffers support monoclonal antibodies, vaccines, mRNA and cell & gene therapy - explore the full GMP-grade catalogue or use the Smart Product Search.