Histidine 100 mM
100 mM histidine buffer for polishing and final formulation of biologics. · GMP catalogue product · CT-69510
Histidine 100 mM is a defined histidine buffer for downstream processing. It is used for size-exclusion (SEC) polishing and, most importantly, as the standard final-formulation buffer for many biologics. As a GMP-grade buffer it is applied across monoclonal antibodies, vaccines, mRNA and cell & gene therapy.
One GMP quality. Histidine 100 mM is a GMP-grade catalogue product (CT-69510), manufactured by PAN-Celltech and released against a defined quality-control panel on every lot.
Why
- Standard formulation base – The common histidine formulation buffer for biologics.
- Polishing & formulation – SEC polishing plus final formulation.
- GMP grade – Catalogue GMP quality, released per lot.
- Multi-application – Used across antibody and C&G formulation.
Specification
| Composition | 100 mM histidine |
| Form | Ready-to-use buffer |
| Storage | 15-25 °C (room temperature) |
| Grade | GMP |
Ordering
| Grade | Article No. | Pack size |
|---|---|---|
| GMP | CT-69510 | 100 ml |
Other pack sizes are available on request.
Beyond compendial – on request. Every PAN downstream buffer is also available in a beyond-compendial version produced with WFI Beyond – Water for Injection engineered beyond the Ph. Eur./USP monograph – for the most demanding endotoxin and purity requirements. Available on request.
In the process – by application (upstream & downstream)
Histidine 100 mM is used at the following process steps across the biologics platforms it supports:
Monoclonal antibodies
- SEC polishing – running buffer.
- Drug-substance formulation – primary final-formulation buffer.
Vaccines
- Formulation – buffering.
mRNA
- Final drug-product / LNP formulation – formulation buffering.
Cell & gene therapy
- Vector final formulation – formulation buffering.
Frequently asked questions
What is Histidine 100 mM used for?
It is used for SEC polishing and as a standard final-formulation buffer for biologics.
Is it multi-application?
Yes, it is used across monoclonal antibodies, vaccines, mRNA and cell & gene therapy downstream, wherever a histidine formulation buffer is required.
One partner across every application. The same GMP downstream buffers support monoclonal antibodies, vaccines, mRNA and cell & gene therapy – explore the full GMP-grade catalogue or use the Smart Product Search.
Related: WFI Quality Water (CT-991500) · DPBS w/o Ca & Mg (CT-36500) · GMP-Grade Products