Magnesium Chloride 1 M
1 M magnesium-chloride concentrate – nuclease and IVT cofactor and general divalent-cation additive. · GMP catalogue product · CT-75100
Magnesium Chloride 1 M is a defined divalent-cation concentrate. It provides the magnesium cofactor for endonuclease digestion in downstream processing and for in-vitro transcription in mRNA production, and serves as a general buffer additive across cell & gene therapy, mRNA and vaccine workflows.
One GMP quality. Magnesium Chloride 1 M is a GMP-grade catalogue product (CT-75100), manufactured by PAN-Celltech and released against a defined quality-control panel on every lot.
Why
- Nuclease cofactor – enables endonuclease / DNase digestion.
- IVT cofactor – for mRNA in-vitro transcription.
- GMP grade – for regulated processing.
- Multi-application – C&G, mRNA and vaccine.
Specification
| Composition | 1 M magnesium chloride |
| Storage | 15-25 °C (room temperature) |
| Form | Stock concentrate |
| Grade | GMP |
Ordering
| Grade | Article No. | Pack size |
|---|---|---|
| GMP | CT-75100 | 100 ml |
Other pack sizes are available on request.
Beyond compendial – on request. Every PAN downstream buffer is also available in a beyond-compendial version produced with WFI Beyond – Water for Injection engineered beyond the Ph. Eur./USP monograph – for the most demanding endotoxin and purity requirements. Available on request.
In the process – by application (upstream & downstream)
Magnesium Chloride 1 M is used at the following process steps across the biologics platforms it supports:
Vaccines
- Nuclease digestion – magnesium cofactor.
mRNA
- In-vitro transcription (USP) – reaction cofactor.
- DNase digestion (DSP) – cofactor for template removal.
Cell & gene therapy
- Nuclease digestion – magnesium cofactor.
- Buffer additive – divalent-cation supplementation.
Frequently asked questions
What is Magnesium Chloride 1 M used for?
It provides the magnesium cofactor for nuclease digestion and in-vitro transcription, and is a general divalent-cation additive.
One partner across every application. The same GMP downstream buffers support monoclonal antibodies, vaccines, mRNA and cell & gene therapy – explore the full GMP-grade catalogue or use the Smart Product Search.
Related: WFI Quality Water (CT-991500) · DPBS w/o Ca & Mg (CT-36500) · GMP-Grade Products