Magnesium Chloride 1 M solution
1 M magnesium-chloride concentrate — cofactor for endonuclease digestion and a general divalent-cation additive. · GMP catalogue product · CT-75100
Magnesium Chloride 1 M is a defined divalent-cation concentrate. It serves as the cofactor for endonuclease digestion in downstream processing and as a general Mg2+ additive — including as an IVT reaction cofactor in mRNA.
Why
- Endonuclease cofactor — activates nuclease digestion.
- Divalent-cation additive — general Mg2+ source.
- GMP grade — for regulated processing.
- Multi-application — mRNA, cell & gene therapy and vaccines.
Specification
| Composition | 1 M magnesium chloride (MgCl2) |
| Storage | 15-25 °C (room temperature) |
| Form | Stock concentrate |
| Grade | GMP |
Ordering
| Grade | Article No. | Pack size |
|---|---|---|
| GMP | CT-75100 | 100 ml |
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Other pack sizes are available on request.
In the downstream process — by application
Magnesium Chloride 1 M solution is used at the following process steps across the biologics platforms it supports:
mRNA
- IVT reaction — Mg2+ cofactor for in-vitro transcription.
Cell & gene therapy
- Nuclease digestion — Mg2+ cofactor for endonuclease treatment.
Vaccines
- Buffers / additives — divalent-cation additive.
Frequently asked questions
What is Magnesium Chloride 1 M used for?
It is a 1 M MgCl2 concentrate — cofactor for endonuclease digestion and a general divalent-cation additive, including as an IVT cofactor in mRNA.
How is it stored?
At 15-25 °C (room temperature).
Related: WFI Quality Water (CT-991500) · DPBS w/o Ca & Mg (CT-36500) · GMP-Grade Products