Potassium acetate 3 M, pH 5.5
3 M potassium acetate at pH 5.5 for alkaline-lysis neutralisation in plasmid-DNA purification. · GMP catalogue product · CT-76500
Potassium acetate 3 M, pH 5.5 is a defined stock for plasmid-DNA (pDNA) purification. It neutralises the alkaline-lysis step and precipitates cell debris and genomic DNA – used in plasmid processing for cell & gene therapy and for mRNA DNA-template production.
One GMP quality. Potassium acetate 3 M, pH 5.5 is a GMP-grade catalogue product (CT-76500), manufactured by PAN-Celltech and released against a defined quality-control panel on every lot.
Why
- Alkaline-lysis neutralisation – for plasmid-DNA purification.
- Debris precipitation – clarifies the lysate.
- GMP grade – for regulated processing.
- Plasmid focus – C&G and mRNA template.
Specification
| Composition | 3 M potassium acetate |
| pH | 5.5 |
| Storage | 15-25 °C (room temperature) |
| Form | Stock concentrate |
| Grade | GMP |
Ordering
| Grade | Article No. | Pack size |
|---|---|---|
| GMP | CT-76500 | 500 ml |
Other pack sizes are available on request.
Beyond compendial – on request. Every PAN downstream buffer is also available in a beyond-compendial version produced with WFI Beyond – Water for Injection engineered beyond the Ph. Eur./USP monograph – for the most demanding endotoxin and purity requirements. Available on request.
In the process – by application (upstream & downstream)
Potassium acetate 3 M, pH 5.5 is used at the following process steps across the biologics platforms it supports:
mRNA
- DNA-template (pDNA) production – alkaline-lysis neutralisation.
Cell & gene therapy
- Plasmid DNA – alkaline-lysis neutralisation and debris precipitation.
Frequently asked questions
What is Potassium acetate 3 M used for?
It neutralises the alkaline-lysis step in plasmid-DNA purification and precipitates debris.
What is the pH?
It is supplied at pH 5.5.
One partner across every application. The same GMP downstream buffers support monoclonal antibodies, vaccines, mRNA and cell & gene therapy – explore the full GMP-grade catalogue or use the Smart Product Search.
Related: WFI Quality Water (CT-991500) · DPBS w/o Ca & Mg (CT-36500) · GMP-Grade Products