Potassium acetate 3 M, pH 5.5
3 M potassium acetate at pH 5.5 for alkaline-lysis neutralisation in plasmid-DNA purification. · GMP (CT-76500)
Potassium acetate 3 M, pH 5.5 is a defined stock for plasmid-DNA (pDNA) purification. It neutralises the alkaline-lysis step and precipitates cell debris and genomic DNA – used in plasmid processing for cell & gene therapy and for mRNA DNA-template production.
One GMP quality. Potassium acetate 3 M, pH 5.5 is a GMP-grade catalogue product (CT-76500), manufactured by PAN-Celltech and released against a defined quality-control panel on every lot.
Why
- Alkaline-lysis neutralisation – for plasmid-DNA purification.
- Debris precipitation – clarifies the lysate.
- GMP grade – for regulated processing.
- Plasmid focus – C&G and mRNA template.
Specification
| Composition | 3 M potassium acetate |
| pH | 5.5 |
| Storage | 15-25 °C (room temperature) |
| Form | Stock concentrate |
| Grade | GMP |
Ordering
| Grade | Art. No. | Pack size |
|---|---|---|
| GMP | CT-76500 | 500 ml |
Other pack sizes are available on request.
Beyond compendial – on request. Every PAN buffer and stock solution is also available in a beyond-compendial version produced with WFI Beyond – Water for Injection engineered beyond the Ph. Eur./USP monograph – for the most demanding endotoxin and purity requirements. Available on request.
In the process – by application (upstream & downstream)
Potassium acetate 3 M, pH 5.5 is used at the following process steps across the biologics platforms it supports:
mRNA
- DNA-template (pDNA) production – alkaline-lysis neutralisation.
Cell & gene therapy
- Plasmid DNA – alkaline-lysis neutralisation and debris precipitation.
Liposomes & LNP
- Aqueous / buffer preparation – concentrated acetate buffer (K+ form) for hydration / loading.
Frequently asked questions
What is Potassium acetate 3 M used for?
It neutralises the alkaline-lysis step in plasmid-DNA purification and precipitates debris.
What is the pH?
It is supplied at pH 5.5.
In which grade is Potassium acetate 3 M available?
It is available as a GMP product (CT-76500).
One partner across every application. The same GMP downstream buffers support monoclonal antibodies, vaccines, mRNA, cell & gene therapy and liposomes & LNP – explore the full GMP-grade catalogue or use the Smart Product Search.
Related: WFI Quality Water (CT-991500) · DPBS w/o Ca & Mg (CT-36500) · GMP-Grade Products