Defibrinated Human Platelet Lysate (hPL)
Defibrinated human platelet lysate (hPL) – a xeno-free alternative to FBS. · Xeno-free growth supplement · RUO (P40-28050)
Defibrinated Human Platelet Lysate (hPL) is a xeno-free, human-derived alternative to fetal bovine serum. It is a rich source of bioactive growth factors (such as PDGF, bFGF, TGF-beta and IGF-1) and promotes the expansion of human adherent and non-adherent primary cells and cell lines, including mesenchymal stromal cells (MSCs). As it is fully defibrinated it is ready to use and requires no additional heparin.
PAN-Biotech quality. Defibrinated Human Platelet Lysate (hPL) is manufactured by PAN-Biotech / PAN-Celltech and released against a defined quality-control panel.
Why
- Xeno-free FBS alternative – human-derived, no animal serum.
- Rich in growth factors – bioactive substances for cell growth.
- Defibrinated – ready for supplementation.
- MSC expansion – suited to MSC-based therapy.
Specification
| Composition | Defibrinated human platelet lysate |
| Role | FBS alternative / growth supplement |
| Form | Liquid |
| Grade | RUO |
| Storage | -20 °C |
Ordering
| Grade | Art. No. | Pack size |
|---|---|---|
| RUO | P40-28050 | 50 ml |
Other pack sizes are available on request.
In the process – by application (upstream & downstream)
Defibrinated Human Platelet Lysate (hPL) is used at the following process steps across the biologics platforms it supports:
Cell & gene therapy
- Serum & serum-free supplements – Xeno-free growth supplement (MSC).
Frequently asked questions
What is hPL used for?
As a xeno-free alternative to FBS for cell expansion, rich in growth factors.
How is it stored?
At -20 °C.
In which grade is Defibrinated Human Platelet Lysate available?
It is available as a RUO product (P40-28050); a matching GMP grade is available on request.
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Related: Cell & Gene Therapy · Cell-Specific Media