Phosphate Buffer 100 mM
100 mM phosphate buffer for anion-exchange, polishing and formulation buffer systems. · GMP (CT-18810) (100 ml) · CT-18850 (500 ml)
Phosphate Buffer 100 mM is a defined phosphate buffer for downstream processing. It is a versatile base for anion-exchange (AEX), polishing and formulation buffer systems. As a GMP-grade buffer it is used across monoclonal antibodies, vaccines, mRNA and cell & gene therapy.
One GMP quality. Phosphate Buffer 100 mM is a GMP-grade catalogue product (CT-18810), manufactured by PAN-Celltech and released against a defined quality-control panel on every lot.
Why
- Versatile phosphate base – AEX, polishing and formulation.
- Defined composition – 100 mM phosphate system.
- GMP grade – Catalogue GMP quality, released per lot.
- Multi-application – Used across antibody, vaccine, mRNA and C&G downstream.
Specification
| Composition | 100 mM phosphate |
| Form | Ready-to-use buffer |
| Storage | 15-25 °C (room temperature) |
| Grade | GMP |
Ordering
Beyond compendial – on request. Every PAN downstream buffer is also available in a beyond-compendial version produced with WFI Beyond – Water for Injection engineered beyond the Ph. Eur./USP monograph – for the most demanding endotoxin and purity requirements. Available on request.
In the process – by application (upstream & downstream)
Phosphate Buffer 100 mM is used at the following process steps across the biologics platforms it supports:
Monoclonal antibodies
- Anion exchange (AEX) – equilibration and wash buffer base.
- SEC polishing – running buffer.
- Formulation – phosphate buffer base.
Vaccines
- Ion-exchange chromatography – buffer base.
- Formulation – phosphate buffering.
mRNA
- Buffer exchange – phosphate buffering.
- Formulation – buffer base.
Cell & gene therapy
- Anion exchange – equilibration and wash.
- Polishing / formulation – buffer base.
Liposomes & LNP
- Aqueous / buffer preparation, size reduction, solvent removal & buffer exchange, purification and formulation & stabilisation – phosphate base for hydration, running, diafiltration, purification and formulation buffers.
Frequently asked questions
What is Phosphate Buffer 100 mM used for?
It is a base for anion-exchange (AEX), polishing and formulation buffer systems.
Is it multi-application?
Yes, it is used across monoclonal antibodies, vaccines, mRNA and cell & gene therapy downstream.
In which grade is Phosphate Buffer 100 mM available?
It is available as a GMP product in two pack sizes: CT-18810 (100 ml) and CT-18850 (500 ml).
One partner across every application. The same GMP downstream buffers support monoclonal antibodies, vaccines, mRNA, cell & gene therapy and liposomes & LNP – explore the full GMP-grade catalogue or use the Smart Product Search.
Related: WFI Quality Water (CT-991500) · DPBS w/o Ca & Mg (CT-36500) · GMP-Grade Products