Upstream & Downstream

Triton X-100 10 % solution

10 % non-ionic detergent concentrate – cell/virus lysis, enveloped-virus inactivation and membrane solubilisation. · GMP catalogue product · CT-01001

GMP · CT-01001
Downstream · DSP

Triton X-100 10 % solution is a defined non-ionic detergent concentrate for downstream processing. It is used for cell and virus lysis, enveloped-virus inactivation and membrane solubilisation across vaccine and cell & gene therapy processes, and for detergent-based viral inactivation in antibody workflows.

One GMP quality. Triton X-100 10 % solution is a GMP-grade catalogue product (CT-01001), manufactured by PAN-Celltech and released against a defined quality-control panel on every lot.

Why

  • Lysis & solubilisation – cell/virus lysis and membrane solubilisation.
  • Viral inactivation – enveloped-virus inactivation.
  • GMP grade – for regulated processing.
  • Multi-application – vaccine, C&G and mAb.

Specification

Composition 10 % (v/v) Triton X-100
Storage 15-25 °C (room temperature)
Form Detergent concentrate
Grade GMP

Ordering

Grade Article No. Pack size
GMP CT-01001 100 ml

Other pack sizes are available on request.

Beyond compendial – on request. Every PAN downstream buffer is also available in a beyond-compendial version produced with WFI Beyond – Water for Injection engineered beyond the Ph. Eur./USP monograph – for the most demanding endotoxin and purity requirements. Available on request.

In the process – by application (upstream & downstream)

Triton X-100 10 % solution is used at the following process steps across the biologics platforms it supports:

Monoclonal antibodies

  • Viral inactivation – detergent-based inactivation step.

Vaccines

  • Cell/virus lysis – release of product.
  • Enveloped-virus inactivation – split / inactivation step.

Cell & gene therapy

  • Cell/virus lysis – vector release.
  • Enveloped-virus inactivation – viral safety step.
  • Membrane solubilisation – processing of membrane-associated product.

Frequently asked questions

What is Triton X-100 10 % used for?

It is used for cell/virus lysis, enveloped-virus inactivation and membrane solubilisation.

One partner across every application. The same GMP downstream buffers support monoclonal antibodies, vaccines, mRNA and cell & gene therapy – explore the full GMP-grade catalogue or use the Smart Product Search.