Upstream & Downstream

Acetic acid 1 M

1 M acetic acid concentrate for pH adjustment / acidification in buffer preparation – liposome & LNP aqueous phase. · GMP (CT-88500)

GMP · CT-88500
Upstream · USP

Acetic acid 1 M is a defined acidification concentrate for buffer preparation. It sets and fine-tunes the pH of acetate- and citrate-based buffer systems in the aqueous / buffer-preparation phase of liposome and lipid-nanoparticle (LNP) manufacturing, and in general buffer preparation with acetate and citrate systems.

One GMP quality. Acetic acid 1 M is a GMP-grade catalogue product (CT-88500), manufactured by PAN-Celltech and released against a defined quality-control panel on every lot.

Why

  • pH adjustment / acidification – sets and fine-tunes acetate and citrate buffer systems.
  • Ready to use – defined 1 M concentrate, no weighing or dilution of glacial acetic acid.
  • GMP grade – for regulated buffer preparation.

Specification

Composition 1 M acetic acid (~6 % w/v)
Function Acidification / pH-adjustment concentrate
Storage 15-25 °C (room temperature)
RNase / DNase Tested RNase- and DNase-free
Form Stock concentrate
Grade GMP

Ordering

Grade Art. No. Pack size
GMP CT-88500 500 ml

Other pack sizes are available on request.

Beyond compendial – on request. Like every PAN buffer and stock solution, Acetic acid 1 M is also available in a beyond-compendial version produced with WFI Beyond – Water for Injection engineered beyond the Ph. Eur./USP monograph – for the most demanding endotoxin and purity requirements. Available on request.

In the process – by application (upstream & downstream)

Acetic acid 1 M is used at the following process steps across the biologics platforms it supports:

Liposomes & LNP

  • Aqueous / buffer preparation – acetate-buffer preparation and pH adjustment for nucleic-acid loading / mixing.

Frequently asked questions

What is Acetic acid 1 M used for?

It is a defined acidification / pH-adjustment concentrate for buffer preparation – for example in the aqueous / buffer-preparation phase of liposome and LNP manufacturing, and in general buffer preparation with acetate and citrate systems.

Is Acetic acid 1 M RNase- and DNase-free?

Yes. Acetic acid 1 M is tested RNase- and DNase-free. This matters in liposome and LNP manufacturing, where the acidic aqueous phase prepared with it carries the nucleic-acid payload during particle formation.

In which grade is Acetic acid 1 M available?

It is available as a GMP product (CT-88500, 500 ml); other pack sizes are available on request.

One partner across every application. The same GMP downstream buffers support monoclonal antibodies, vaccines, mRNA, cell & gene therapy and liposomes & LNP – explore the full GMP-grade catalogue or use the Smart Product Search.