Upstream & Downstream

IL-2 human rec.

Recombinant human interleukin-2 – cytokine for T- and NK-cell proliferation. · Recombinant cytokine · RUO (CB-2130203)

RUO · CB-2130203
Upstream · USP

Interleukin-2 (IL-2) is a powerful immune-regulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signalling is required for T-cell proliferation and other functions essential for the immune response. IL-2 also stimulates the growth and differentiation of B-cells, NK-cells, lymphokine-activated killer cells, monocytes and macrophages.

PAN-Biotech quality. IL-2 human rec. is manufactured by PAN-Biotech / PAN-Celltech and released against a defined quality-control panel.

Why

  • T-/NK-cell proliferation – immune-cell expansion.
  • Recombinant human – E. coli-produced, 15.5 kDa.
  • Media supplement – for immune-cell media.
  • Research grade – RUO biological.

Specification

Composition Recombinant human IL-2, 134 aa, 15.5 kDa (one disulfide bond)
Source E. coli, recombinant
Form Lyophilised powder
Grade RUO
Storage -20 °C

Ordering

Grade Art. No. Pack size
RUO CB-2130203 10 µg

Other pack sizes are available on request.

In the process – by application (upstream & downstream)

IL-2 human rec. is used at the following process steps across the biologics platforms it supports:

Cell & gene therapy

  • Cytokines & growth factors – T-/NK-cell proliferation.
  • Genetic modification / Transduction – T-cell activation cytokine.

Frequently asked questions

What is IL-2 used for?

As a cytokine supplement to drive T- and NK-cell proliferation.

How is it supplied?

As a recombinant human protein (lyophilised), stored at -20 °C.

In which grade is IL-2 human rec. available?

It is available as a RUO product (CB-2130203); a GMP grade is not available.

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