LIF human rec.
Recombinant human LIF – stem-cell pluripotency maintenance. · Recombinant cytokine / growth factor · RUO (CB-1106001)
Leukemia Inhibitory Factor, also called LIF, is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. LIF has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone and fat metabolism, mitogenesis of factor dependent cell lines and promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78% identity in its amino acid sequence. Human recombinant LIF
PAN-Biotech quality. LIF human rec. is manufactured by PAN-Biotech / PAN-Celltech and released against a defined quality-control panel.
Why
- Recombinant human – defined biological.
- Cell expansion – stem-cell pluripotency maintenance.
- Media supplement – for defined media.
- Research grade – RUO biological.
Specification
| Composition | Recombinant human LIF |
| Source | E. coli, recombinant |
| Form | Lyophilised powder |
| Grade | RUO |
| Storage | -20 °C |
Ordering
| Grade | Art. No. | Pack size |
|---|---|---|
| RUO | CB-1106001 | 10 µg |
Other pack sizes are available on request.
In the process – by application (upstream & downstream)
LIF human rec. is used at the following process steps across the biologics platforms it supports:
Cell & gene therapy
- Cytokines & growth factors – Stem-cell self-renewal.
Frequently asked questions
What is LIF human rec. used for?
As a supplement to support stem-cell pluripotency maintenance.
How is it stored?
At -20 °C (lyophilised).
In which grade is LIF human rec. available?
It is available as a RUO product (CB-1106001); a GMP grade is not available.
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Related: Cell & Gene Therapy · Cell-Specific Media