Upstream & Downstream

Potassium acetate 3 M, pH 5.5

3 M potassium-acetate concentrate at pH 5.5 — alkaline-lysis neutralisation for plasmid-DNA (pDNA) processing. · GMP catalogue product · CT-76500

GMP · CT-76500Downstream · DSP

Potassium acetate 3 M, pH 5.5 is a defined concentrate for plasmid-DNA processing. It neutralises the alkaline-lysis step in pDNA purification, precipitating SDS and cell debris while the plasmid stays in solution.

One GMP quality. Potassium acetate 3 M, pH 5.5 is a GMP-grade catalogue product (CT-76500), manufactured by PAN-Celltech and released against a defined quality-control panel on every lot.

Why

  • Alkaline-lysis neutralisation — neutralises the lysis step in pDNA prep.
  • pDNA processing — precipitates SDS, protein and debris.
  • GMP grade — for regulated processing.
  • Multi-application — cell & gene therapy and mRNA (template).

Specification

Composition3 M potassium acetate
pH5.5
Storage15-25 °C (room temperature)
FormStock concentrate
GradeGMP

Ordering

GradeArticle No.Pack size
GMPCT-76500500 ml

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Other pack sizes are available on request.

Beyond compendial — on request. Every PAN downstream product is also available in a beyond-compendial version produced with WFI Beyond — Water for Injection engineered beyond the Ph. Eur./USP monograph — for the most demanding endotoxin and purity requirements. Available on request.

In the downstream process — by application

Potassium acetate 3 M, pH 5.5 is used at the following process steps across the biologics platforms it supports:

Cell & gene therapy

  • pDNA purification — alkaline-lysis neutralisation and precipitation.

mRNA

  • pDNA template preparation — neutralisation in plasmid template purification.

Frequently asked questions

What is Potassium acetate 3 M used for?

It neutralises the alkaline-lysis step in plasmid-DNA (pDNA) purification, precipitating SDS, protein and debris.

What is the pH?

It is supplied at pH 5.5.

One partner across every application. The same GMP downstream products support monoclonal antibodies, vaccines, mRNA and cell & gene therapy — explore the full GMP-grade catalogue or use the Smart Product Search.