Upstream & Downstream

Triton X-100 10 % Solution

10 % non-ionic detergent concentrate - cell/virus lysis, enveloped-virus inactivation and membrane solubilisation. · GMP catalogue product · CT-01001

GMP · CT-01001Downstream · DSP

Triton X-100 10 % Solution is a defined non-ionic detergent concentrate for downstream processing. It is used for cell and virus lysis, enveloped-virus inactivation and membrane solubilisation across vaccine and cell & gene therapy processes, and for detergent-based viral inactivation in antibody workflows.

One GMP quality. Triton X-100 10 % Solution is a GMP-grade catalogue product (CT-01001), manufactured by PAN-Celltech and released against a defined quality-control panel on every lot.

Why

  • Lysis & solubilisation - cell/virus lysis and membrane solubilisation.
  • Viral inactivation - enveloped-virus inactivation.
  • GMP grade - for regulated processing.
  • Multi-application - vaccine, C&G and mAb.

Specification

Composition10 % (v/v) Triton X-100
Storage15-25 °C (room temperature)
FormDetergent concentrate
GradeGMP

Ordering

GradeArticle No.Pack size
GMPCT-01001100 ml

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Other pack sizes are available on request.

Beyond compendial - on request. Every PAN downstream buffer is also available in a beyond-compendial version produced with WFI Beyond - Water for Injection engineered beyond the Ph. Eur./USP monograph - for the most demanding endotoxin and purity requirements. Available on request.

In the downstream process - by application

Triton X-100 10 % Solution is used at the following process steps across the four biologics platforms:

Monoclonal antibodies

  • Viral inactivation - detergent-based inactivation step.

Vaccines

  • Cell/virus lysis - release of product.
  • Enveloped-virus inactivation - split / inactivation step.

mRNA

  • Not typically used in this modality.

Cell & gene therapy

  • Cell/virus lysis - vector release.
  • Enveloped-virus inactivation - viral safety step.
  • Membrane solubilisation - processing of membrane-associated product.

Frequently asked questions

What is Triton X-100 10 % used for?

It is used for cell/virus lysis, enveloped-virus inactivation and membrane solubilisation.

One partner across every application. The same GMP downstream buffers support monoclonal antibodies, vaccines, mRNA and cell & gene therapy - explore the full GMP-grade catalogue or use the Smart Product Search.