Upstream & Downstream

EDTA 0.5 M, pH 8.0

0.5 M EDTA stock at pH 8.0 for chelation - TE buffer, reaction stop and equilibration additive. · GMP catalogue product · CT-10500

GMP · CT-10500Downstream · DSP

EDTA 0.5 M, pH 8.0 is a defined chelator concentrate for downstream processing. It is used as a component of TE buffer, as a reaction-stop and metal-chelation additive, and to control trace metals in buffers and formulation - across mRNA, cell & gene therapy and antibody workflows.

One GMP quality. EDTA 0.5 M, pH 8.0 is a GMP-grade catalogue product (CT-10500), manufactured by PAN-Celltech and released against a defined quality-control panel on every lot.

Why

  • Metal chelation - controls trace metals; stops metal-dependent reactions.
  • TE buffer component - for nucleic-acid handling.
  • GMP grade - for regulated processing.
  • Multi-application - mRNA, C&G and mAb.

Specification

Composition0.5 M EDTA
pH8.0
Storage15-25 °C (room temperature)
FormStock concentrate
GradeGMP

Ordering

GradeArticle No.Pack size
GMPCT-10500500 ml

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Other pack sizes are available on request.

Beyond compendial - on request. Every PAN downstream buffer is also available in a beyond-compendial version produced with WFI Beyond - Water for Injection engineered beyond the Ph. Eur./USP monograph - for the most demanding endotoxin and purity requirements. Available on request.

In the downstream process - by application

EDTA 0.5 M, pH 8.0 is used at the following process steps across the four biologics platforms:

Monoclonal antibodies

  • Buffers / formulation - trace-metal control (chelation additive).

Vaccines

  • Buffers - chelation additive.

mRNA

  • TE buffer - nucleic-acid handling component.
  • Reaction stop / stabilisation - metal chelation and nuclease inhibition.

Cell & gene therapy

  • TE buffer - plasmid / nucleic-acid handling.
  • Chelation - metal control in processing.

Frequently asked questions

What is EDTA 0.5 M used for?

It is a chelation additive - TE buffer component, reaction stop and trace-metal control.

What is the pH?

It is supplied at pH 8.0.

One partner across every application. The same GMP downstream buffers support monoclonal antibodies, vaccines, mRNA and cell & gene therapy - explore the full GMP-grade catalogue or use the Smart Product Search.