Upstream & Downstream

Ammonium Sulfate 3 M

High-concentration 3 M ammonium sulfate stock for flexible high-salt loading in HIC. · GMP catalogue product · CT-68500

GMP · CT-68500Downstream · DSP

Ammonium Sulfate 3 M is a high-concentration ammonium-sulfate stock for downstream processing. It enables HIC loading at higher salt strengths than the 1 M stock and is used for salt precipitation. As a GMP-grade stock it is applied across monoclonal antibodies, vaccines, mRNA and cell & gene therapy.

One GMP quality. Ammonium Sulfate 3 M is a GMP-grade catalogue product (CT-68500), manufactured by PAN-Celltech and released against a defined quality-control panel on every lot.

Why

  • Higher salt strength - Flexible HIC loading beyond the 1 M stock.
  • Also for precipitation - Salt precipitation / conditioning.
  • GMP grade - Catalogue GMP quality, released per lot.
  • Multi-application - Used across antibody, vaccine and C&G downstream.

Specification

Composition3 M ammonium sulfate
FormStock concentrate
Storage15-25 °C (room temperature)
GradeGMP

Ordering

GradeArticle No.Pack size
GMPCT-68500500 ml

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Other pack sizes are available on request.

Beyond compendial - on request. Every PAN downstream buffer is also available in a beyond-compendial version produced with WFI Beyond - Water for Injection engineered beyond the Ph. Eur./USP monograph - for the most demanding endotoxin and purity requirements. Available on request.

In the downstream process - by application

Ammonium Sulfate 3 M is used at the following process steps across the four biologics platforms:

Monoclonal antibodies

  • HIC - high-salt loading and conditioning.

Vaccines

  • HIC - high-salt loading.
  • Concentration - salt precipitation.

mRNA

  • Not typically used in this modality.

Cell & gene therapy

  • HIC - high-salt loading.
  • Concentration - precipitation.

Frequently asked questions

What is Ammonium Sulfate 3 M used for?

It enables HIC loading at higher salt strengths and is used for salt-precipitation steps.

Is it multi-application?

Yes, it is used across monoclonal antibodies, vaccines, mRNA and cell & gene therapy downstream.

One partner across every application. The same GMP downstream buffers support monoclonal antibodies, vaccines, mRNA and cell & gene therapy - explore the full GMP-grade catalogue or use the Smart Product Search.